 |
 |
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| 20.08.2005 | Eordaikos | - | Anagennisi Karditsa | 0:1 | ||
| Keratsini | - | Doxa Dramas FC | 2:4 i.E. | |||
| AE Giannena | - | PAE Thraki Alexandroupoli | 1:4 | |||
| Thyella Patros | - | Ionia 2000 Chania | 4:1 | |||
| Agrotikos Asteras | - | Vyzas FC | 6:2 | |||
| 21.08.2005 | Lamia | - | Ethnikos Piraeus | 1:2 | ||
| Achaiki | - | Asteras Tripolis | 1:2 | |||
| Panetolikos | - | Eolikos | 6:7 i.E. | |||
| PAS Giannina | - | Apollon Smyrnis | 3:0 | |||
| Lilas FC | - | Panthrakikos | 2:4 i.E. | |||
| Pierikos Katerini | - | Messiniakos GC | 3:0 | |||
| Anagennisi Arta | - | Acharnaikos FC | 2:1 | |||
| AO Trikala | - | Kozani FC | 2:1 | |||
| 24.08.2005 | Diagoras FC | - | Thermaikos FC | 3:0 | ||
| Polykastro FC | - | Atsalenios | 2:0 | |||
| AO Kavala | - | AS Rhodos | 3:0 |
