23.07.2021 20:45 Wexford FC - Cabinteely FC 3:0
20:45 UC Dublin - Shelbourne FC 2:0
20:45 Athlone Town - Waterford FC 2:4 (0:1, 3:3, 4:4) i.E.
20:45 St Patrick's Athletic - Bray Wanderers 6:0
21:00 St. Kevin's Boys - Kilnamanagh AFC 1:4
21:00 Shamrock Rovers - Galway United 2:0
21:00 Maynooth University Town - Malahide United 4:0
24.07.2021 16:00 Drogheda United - Derry City 2:4 (1:0, 1:1, 1:1) i.E.
17:00 Fairview Rangers - Finn Harps 0:3 (0:0) n.V.
20:30 Longford Town - Bangor GG FC 5:0 (1:0)
25.07.2021 12:00 Killester Donnycarney FC - Usher Celtic -:-
15:00 Liffey Wanderers - Cobh Ramblers -:-
15:00 Crumlin United - St. Mochta's -:-
15:00 Treaty United - Dundalk FC -:-
16:00 College Corinthians - Bohemian FC -:-
18:00 Sligo Rovers - Cork City -:-