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| H | FK Rabotnički | - | Napredok Kičevo | 4:1 (2:1) | ||
| R | Napredok Kičevo | - | FK Rabotnički | 0:3 (0:2) | ||
| H: 19.10.2011 14:00 | R: 16.11.2011 13:00 | Sieger: FK Rabotnički | ||||
| H | FK Turnovo | - | FK Bregalnica Štip | 3:1 (0:1) | ||
| R | FK Bregalnica Štip | - | FK Turnovo | 0:0 (0:0) | ||
| H: 19.10.2011 14:00 | R: 09.11.2011 13:00 | Sieger: FK Turnovo | ||||
| H | FK Renova | - | FK Teteks | 6:0 (2:0) | ||
| R | FK Teteks | - | FK Renova | 2:3 (1:2) | ||
| H: 19.10.2011 14:00 | R: 08.11.2011 13:00 | Sieger: FK Renova | ||||
| H | Vardar Skopje | - | 11 Oktomvri | 2:0 (1:0) | ||
| R | 11 Oktomvri | - | Vardar Skopje | 2:1 (0:0) | ||
| H: 19.10.2011 18:00 | R: 09.11.2011 13:00 | Sieger: Vardar Skopje | ||||
