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| 07.09.2022 | 16:30 | Jedinstvo Bijelo Polje | - | OFK Mladost DG | 3:1 (2:1) | |
| 16:30 | FK Sutjeska | - | FK Jezero | 1:0 (1:0) | ||
| 17:00 | FK Bokelj | - | FK Arsenal | 2:3 (1:0) | ||
| 18:00 | FK Podgorica | - | OSK Igalo | 3:0 (0:0) | ||
| 18:00 | FK KOM Podgorica | - | FK Iskra Danilovgrad | 0:3 (0:2) | ||
| 18:00 | FK Zeta | - | FK Rudar Pljevlja | 1:3 (0:3) | ||
| 19:00 | FK Mornar | - | OFK Petrovac | 2:0 (0:0) | ||
| 19:00 | FK Dečić Tuzi | - | FK Budućnost Podgorica | 5:4 (1:1, 1:1) i.E. |
