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| Liga Nac. | 28.02.2021 | Achuapa | - | Cobán Imperial | 2:1 | ??? |
| Liga Nac. | 07.03.2021 | Achuapa | - | CSD Municipal | 1:2 | ??? |
| Liga Nac. | 13.03.2021 | Achuapa | - | Sacachispas | 2:1 | ??? |
| Liga Nac. | 04.04.2021 | Achuapa | - | Deportivo Guastatoya | 1:0 | ??? |
| Liga Nac. | 11.04.2021 | Achuapa | - | Sanarate | 2:2 | ??? |
| Liga Nac. | 14.04.2021 | Achuapa | - | Xelaju MC | 1:1 | ??? |
| Liga Nac. | 21.04.2021 | Achuapa | - | Antigua GFC | 1:2 | ??? |
| Liga Nac. | 28.04.2021 | Achuapa | - | Iztapa | 0:3 | ??? |
| Liga Nac. | 07.08.2021 | Achuapa | - | Deportivo Malacateco | 0:0 | ??? |
| Liga Nac. | 11.08.2021 | Achuapa | - | Comunicaciones | 1:3 | ??? |
| Liga Nac. | 21.08.2021 | Achuapa | - | Antigua GFC | 0:1 | ??? |
| Liga Nac. | 29.08.2021 | Achuapa | - | Santa Lucía | 0:2 | ??? |
| Liga Nac. | 11.09.2021 | Achuapa | - | Iztapa | 2:0 | ??? |
| Liga Nac. | 25.09.2021 | Achuapa | - | Sololá FC | 0:2 | ??? |
| Liga Nac. | 03.10.2021 | Achuapa | - | Nueva Concepción | 1:0 | ??? |
| Liga Nac. | 23.10.2021 | Achuapa | - | Cobán Imperial | 1:0 | ??? |
| Liga Nac. | 31.10.2021 | Achuapa | - | Deportivo Guastatoya | 0:0 | ??? |
| Liga Nac. | 14.11.2021 | Achuapa | - | CSD Municipal | 0:1 | ??? |
| Liga Nac. | 28.11.2021 | Achuapa | - | Xelaju MC | 0:1 | ??? |
Guatemala