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| 30.07.2022 | 17:00 | Mazatlán FC | - | Atlas Guadalajara | 2:5 (1:2) | |
| 18:30 | Club Necaxa | - | FC Juárez | 8:0 (2:0) | ||
| 18:30 | Deportivo Toluca | - | CF América | 2:1 (0:1) | ||
| 18:30 | Pumas UNAM | - | CF Pachuca | 1:0 (1:0) | ||
| 18:30 | Gallos Blancos | - | Puebla FC | 3:0 (1:0) | ||
| 18:30 | CF Monterrey | - | Club León | 2:2 (2:0) | ||
| 18:45 | Atlético San Luis | - | UANL Tigres | 1:4 (1:0) | ||
| 31.07.2022 | 21:45 | Club Tijuana | - | Deportivo Guadalajara | 3:1 (2:1) |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 5 | 4 | 1 | 0 | 10:6 | 4 | 13 |
| 2 |
|
Deportivo Toluca | 5 | 3 | 2 | 0 | 10:6 | 4 | 11 |
| 3 |
|
Club Necaxa | 5 | 3 | 0 | 2 | 13:4 | 9 | 9 |
| 4 |
|
Gallos Blancos | 6 | 2 | 2 | 2 | 10:7 | 3 | 8 |
| 5 |
|
CF Pachuca | 6 | 2 | 2 | 2 | 6:4 | 2 | 8 |
| 6 |
|
Cruz Azul | 5 | 2 | 0 | 3 | 11:12 | -1 | 6 |
| 7 |
|
Puebla FC | 5 | 2 | 0 | 3 | 9:11 | -2 | 6 |
| 8 |
|
CF América | 5 | 1 | 1 | 3 | 9:12 | -3 | 4 |
| 9 |
|
FC Juárez | 6 | 1 | 0 | 5 | 7:23 | -16 | 3 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Tijuana | 6 | 5 | 1 | 0 | 17:3 | 14 | 16 |
| 2 |
|
Atlas Guadalajara | 6 | 4 | 2 | 0 | 19:5 | 14 | 14 |
| 3 |
|
CF Monterrey | 6 | 3 | 3 | 0 | 18:8 | 10 | 12 |
| 4 |
|
Deportivo Guadalajara | 5 | 3 | 0 | 2 | 6:7 | -1 | 9 |
| 5 |
|
Santos Laguna | 5 | 2 | 0 | 3 | 15:10 | 5 | 6 |
| 6 |
|
Club León | 5 | 1 | 1 | 3 | 6:7 | -1 | 4 |
| 7 |
|
UANL Tigres | 5 | 1 | 1 | 3 | 7:14 | -7 | 4 |
| 8 |
|
Atlético San Luis | 5 | 1 | 0 | 4 | 6:25 | -19 | 3 |
| 9 |
|
Mazatlán FC | 5 | 0 | 0 | 5 | 4:19 | -15 | 0 |
| Playoffs | |
| Playoffs |
