 |
 |
|
| 12.10.2021 | 22:00 | Itabaiana - SE | - | Bahia de Feira - BA | 3:1 (0:1, 1:1, 1:1) i.E. | |
| 13.10.2021 | 02:30 | Treze - PB | - | Floresta - CE | 1:3 (1:2) | |
| 02:30 | Juazeirense - BA | - | Central - PE | 1:0 (0:0) | ||
| 19:00 | Moto Club - MA | - | Retrô - PE | 3:2 (1:0) | ||
| 14.10.2021 | 00:30 | Jacuipense - BA | - | Atlético Cearense - CE | 1:0 (0:0) | |
| 15.10.2021 | 01:00 | ASA - AL | - | Sousa - PB | 1:2 (0:2) | |
| 16.10.2021 | 21:00 | River - PI | - | Lagarto - SE | 5:0 (2:0) | |
| 17.10.2021 | 01:00 | Imperatriz - MA | - | Fluminense - PI | 5:4 (0:0, 1:1, 1:1) i.E. |
