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| H | Deportivo Guadalajara | - | Pumas UNAM | 3:2 (1:0) | ||
| R | Pumas UNAM | - | Deportivo Guadalajara | 1:1 (0:1) | ||
| H: 10.11.2022 17:00 | R: 14.11.2022 00:00 | Sieger: Deportivo Guadalajara | ||||
|
|
|
| H | Deportivo Guadalajara | - | Pumas UNAM | 3:2 (1:0) | ||
| R | Pumas UNAM | - | Deportivo Guadalajara | 1:1 (0:1) | ||
| H: 10.11.2022 17:00 | R: 14.11.2022 00:00 | Sieger: Deportivo Guadalajara | ||||
