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| H | Club Calor | - | Mazorqueros | 1:0 (1:0) | ||
| R | Mazorqueros | - | Club Calor | 0:2 (0:1) | ||
| H: 03.11.2022 02:00 | R: 05.11.2022 23:00 | Sieger: Club Calor | ||||
| H | Pioneros de Cancún | - | Alebrijes de Oaxaca II | 1:2 (0:1) | ||
| R | Alebrijes de Oaxaca II | - | Pioneros de Cancún | 1:0 (0:0) | ||
| H: 03.11.2022 02:00 | R: 06.11.2022 01:00 | Sieger: Alebrijes de Oaxaca II | ||||
