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| 13.04.2018 | 17:00 | Club León II | - | Deportivo Guadalajara II | 0:1 | |
| 17:00 | CF América II | - | Club Irapuato | 1:1 | ||
| 17:00 | Pumas UNAM II | - | Sporting Canamy | 2:2 | ||
| 17:00 | Lobos BUAP II | - | Real Zamora | 2:2 | ||
| 19:00 | Gallos Blancos II | - | Pioneros de Cancún | 0:1 | ||
| 23:00 | Cruz Azul Hidalgo | - | Tuxtla FC | 0:1 | ||
| 14.04.2018 | 00:00 | CF Monterrey II | - | UANL Tigres II | 0:2 | |
| 02:00 | Tecos Fútbol Club | - | Alacranes de Durango | 0:2 | ||
| 03:30 | Deportivo Tepic | - | Pacific F. C. | 0:5 | ||
| 17:00 | Deportivo Toluca II | - | Halcones de Morelos | 0:1 | ||
| 17:00 | Puebla FC II | - | Cruz Azul II | 1:0 | ||
| 18:00 | Santos Laguna II | - | Monarcas Morelia II | 1:1 | ||
| 23:00 | Loros UCOL | - | Club Necaxa II | 4:0 | ||
| 15.04.2018 | 00:00 | Tepatitlán | - | Dorados UACH | 5:0 | |
| 00:00 | Gavilanes de Matamoros | - | Atlas Guadalajara II | 3:1 | ||
| 00:00 | Atlético Reynosa | - | Club Tijuana II | 1:1 | ||
| 17.04.2018 | 00:00 | Inter Playa | - | Reboceros de La Piedad | 1:0 | |
| 19.04.2018 | 18:00 | CD Veracruz II | - | CF Pachuca II | 3:0 |
| 1 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Loros UCOL | 16 | 10 | 3 | 3 | 33:14 | 19 | 35 |
| 2 |
|
Club Necaxa II | 16 | 8 | 4 | 4 | 19:18 | 1 | 29 |
| 3 |
|
UANL Tigres II | 16 | 7 | 5 | 4 | 19:11 | 8 | 27 |
| 4 |
|
Atlas Guadalajara II | 16 | 7 | 5 | 4 | 22:20 | 2 | 27 |
| 5 |
|
Alacranes de Durango | 16 | 7 | 3 | 6 | 22:19 | 3 | 25 |
| 6 |
|
Atlético Reynosa | 16 | 7 | 3 | 6 | 24:12 | 12 | 24 |
| 7 |
|
Tepatitlán | 16 | 6 | 4 | 6 | 22:18 | 4 | 23 |
| 8 |
|
Monarcas Morelia II | 16 | 5 | 7 | 4 | 20:17 | 3 | 23 |
| 9 |
|
Pacific F. C. | 16 | 6 | 4 | 6 | 20:19 | 1 | 23 |
| 10 |
|
Tecos Fútbol Club | 16 | 6 | 4 | 6 | 16:14 | 2 | 22 |
| 11 |
|
Deportivo Guadalajara II | 16 | 5 | 7 | 4 | 15:15 | 0 | 22 |
| 12 |
|
Santos Laguna II | 16 | 6 | 4 | 6 | 21:22 | -1 | 22 |
| 13 |
|
Club León II | 16 | 6 | 2 | 8 | 16:22 | -6 | 20 |
| 14 |
|
Gavilanes de Matamoros | 16 | 4 | 6 | 6 | 15:23 | -8 | 19 |
| 15 |
|
Deportivo Tepic | 16 | 5 | 3 | 8 | 12:27 | -15 | 19 |
| 16 |
|
Club Tijuana II | 16 | 3 | 6 | 7 | 24:27 | -3 | 15 |
| 17 |
|
Dorados UACH | 16 | 4 | 3 | 9 | 16:30 | -14 | 15 |
| 18 |
|
CF Monterrey II | 16 | 2 | 7 | 7 | 14:22 | -8 | 13 |
| 2 | |||||||||
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Tuxtla FC | 16 | 11 | 2 | 3 | 29:12 | 17 | 35 |
| 2 |
|
Reboceros de La Piedad | 16 | 10 | 2 | 4 | 26:15 | 11 | 33 |
| 3 |
|
Club Irapuato | 16 | 8 | 5 | 3 | 31:23 | 8 | 29 |
| 4 |
|
Inter Playa | 16 | 7 | 7 | 2 | 20:14 | 6 | 29 |
| 5 |
|
Pioneros de Cancún | 16 | 9 | 2 | 5 | 16:13 | 3 | 29 |
| 6 |
|
CF América II | 16 | 8 | 2 | 6 | 23:17 | 6 | 27 |
| 7 |
|
Real Zamora | 16 | 6 | 5 | 5 | 20:19 | 1 | 25 |
| 8 |
|
Cruz Azul Hidalgo | 16 | 5 | 5 | 6 | 20:18 | 2 | 21 |
| 9 |
|
Puebla FC II | 16 | 5 | 5 | 6 | 18:21 | -3 | 21 |
| 10 |
|
Gallos Blancos II | 16 | 4 | 7 | 5 | 20:17 | 3 | 20 |
| 11 |
|
Sporting Canamy | 16 | 5 | 5 | 6 | 19:25 | -6 | 20 |
| 12 |
|
CD Veracruz II | 16 | 5 | 4 | 7 | 16:15 | 1 | 19 |
| 13 |
|
Halcones de Morelos | 16 | 4 | 7 | 5 | 13:16 | -3 | 19 |
| 14 |
|
Lobos BUAP II | 16 | 3 | 8 | 5 | 17:24 | -7 | 18 |
| 15 |
|
Cruz Azul II | 16 | 4 | 4 | 8 | 17:25 | -8 | 17 |
| 16 |
|
Deportivo Toluca II | 16 | 3 | 5 | 8 | 14:22 | -8 | 15 |
| 17 |
|
Pumas UNAM II | 16 | 3 | 3 | 10 | 21:31 | -10 | 14 |
| 18 |
|
CF Pachuca II | 16 | 3 | 4 | 9 | 14:27 | -13 | 13 |
