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| 27.11.2020 | 17:00 | Chindia Târgoviște | - | FC Hermannstadt | 4:2 (1:1, 1:1, 1:1) i.E. | |
| 19:45 | Progresul Spartac | - | CS Universitatea Craiova | 0:5 (0:3) | ||
| 28.11.2020 | 10:00 | Turris-Oltul | - | Sepsi OSK | 1:0 (0:0) | |
| 11:00 | CSC Sânmartin | - | FC Dunărea Călărași | 0:1 (0:0) | ||
| 12:15 | FC Universitatea Craiova | - | ASU Poli Timişoara | 1:3 (1:1) | ||
| 12:30 | Farul Constanta | - | Academica Clinceni | 2:1 (1:0) | ||
| 12:30 | Concordia Chiajna | - | FC Botoşani | 0:2 (0:0) | ||
| 12:30 | Pandurii Târgu Jiu | - | Argeș Pitești | 1:0 (0:0) | ||
| 17:00 | Ceahlăul Piatra Neamt | - | Petrolul Ploieşti | 1:2 (1:0) | ||
| 19:45 | Dinamo Bucureşti | - | FC Viitorul Constanța | 3:0 (2:0) | ||
| 29.11.2020 | 11:15 | Ripensia Timisoara | - | Astra Giurgiu | 1:5 (1:1) | |
| 12:30 | Hușana Huși | - | Universitatea Cluj | 2:8 (1:5) | ||
| 16:30 | FC Voluntari | - | Gaz Metan Mediaş | 0:6 (0:1) | ||
| 19:30 | FC Politehnica Iași | - | CFR Cluj | 1:0 (0:0) | ||
| 30.11.2020 | 13:00 | FK Csikszereda | - | UTA Arad | 0:2 (0:2) | |
| 19:45 | Gloria Buzau | - | FC FCSB | 0:3 Wert. |
