 |
 |
|
|
| 15.10.2021 | 17:00 | Tatran Liptovský Mikuláš | - | AS Trenčín | 2:1 (0:0) | |
| 16.10.2021 | 16:00 | MŠK Žilina | - | FC DAC 1904 | 0:2 (0:1) | |
| 18:00 | Zlaté Moravce | - | ŠKF Sereď | 2:2 (1:1) | ||
| 18:00 | FK Pohronie | - | MFK Ružomberok | 2:2 (1:1) | ||
| 18:00 | FK Senica | - | MFK Zemplín Michalovce | 1:1 (0:1) | ||
| 17.10.2021 | 17:00 | Spartak Trnava | - | Slovan Bratislava | 0:3 Wert. |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 11 | 8 | 2 | 1 | 28:8 | 20 | 26 |
| 2 |
|
Spartak Trnava | 11 | 7 | 2 | 2 | 18:7 | 11 | 23 |
| 3 |
|
MFK Ružomberok | 11 | 4 | 6 | 1 | 16:10 | 6 | 18 |
| 4 |
|
FC DAC 1904 | 11 | 5 | 3 | 3 | 18:15 | 3 | 18 |
| 5 |
|
MFK Zemplín Michalovce | 11 | 5 | 2 | 4 | 14:13 | 1 | 17 |
| 6 |
|
AS Trenčín | 11 | 3 | 5 | 3 | 17:14 | 3 | 14 |
| 7 |
|
MŠK Žilina | 11 | 4 | 2 | 5 | 15:14 | 1 | 14 |
| 8 |
|
FK Senica | 11 | 3 | 5 | 3 | 12:16 | -4 | 14 |
| 9 |
|
ŠKF Sereď | 11 | 3 | 3 | 5 | 10:14 | -4 | 12 |
| 10 |
|
Tatran Liptovský Mikuláš | 11 | 3 | 1 | 7 | 16:26 | -10 | 10 |
| 11 |
|
Zlaté Moravce | 11 | 1 | 4 | 6 | 12:24 | -12 | 7 |
| 12 |
|
FK Pohronie | 11 | 1 | 3 | 7 | 10:25 | -15 | 6 |
| Playoffs | |
| Relegation |
