 |
 |
| Viertelfinale | ||||||
|---|---|---|---|---|---|---|
| 24.09.2022 | 21:00 | Columbus Crew 2 | - | Rochester NYFC | 4:1 | |
| 25.09.2022 | 01:00 | Toronto FC 2 | - | Philadelphia Union 2 | 1:0 | |
| 26.09.2022 | 01:30 | St. Louis City SC 2 | - | North Texas SC | 2:0 | |
| 04:30 | Tacoma Defiance | - | Houston Dynamo 2 | 5:4 i.E. | ||
| Halbfinale | ||||||
| 02.10.2022 | 23:00 | Columbus Crew 2 | - | Toronto FC 2 | 4:3 n.V. | |
| 03.10.2022 | 02:30 | St. Louis City SC 2 | - | Tacoma Defiance | 2:1 | |
| Finale | ||||||
| 08.10.2022 | 19:30 | Columbus Crew 2 | - | St. Louis City SC 2 | 4:1 | |
