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| 03.03.2018 | 16:00 | Córdoba CF B | - | CD Badajoz | 1:1 (0:0) | |
| 04.03.2018 | 11:30 | Granada CF B | - | FC Jumilla | 1:1 (0:1) | |
| 12:00 | CD El Ejido 2012 | - | Recreativo Huelva | 0:1 (0:1) | ||
| 12:00 | UD Melilla | - | Écija Balompié | 1:1 (0:1) | ||
| 12:00 | UCAM Murcia CF | - | RB Linense | 1:1 (1:0) | ||
| 12:00 | CF Villanovense | - | Lorca Deportiva | 1:0 (0:0) | ||
| 12:00 | Marbella FC | - | Real Murcia | 1:1 (1:1) | ||
| 12:00 | UD Las Palmas B | - | Extremadura UD | 1:0 (1:0) | ||
| 17:00 | Mérida AD | - | Real Betis B | 3:1 (1:0) | ||
| 18:30 | San Fernando CD | - | FC Cartagena | 0:2 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Marbella FC | 28 | 15 | 7 | 6 | 40:22 | 18 | 52 |
| 2 |
|
FC Cartagena | 28 | 15 | 7 | 6 | 37:26 | 11 | 52 |
| 3 |
|
Extremadura UD | 28 | 13 | 7 | 8 | 41:25 | 16 | 46 |
| 4 |
|
Real Murcia | 28 | 11 | 10 | 7 | 33:23 | 10 | 43 |
| 5 |
|
Granada CF B | 28 | 11 | 9 | 8 | 27:24 | 3 | 42 |
| 6 |
|
UCAM Murcia CF | 28 | 11 | 9 | 8 | 28:27 | 1 | 42 |
| 7 |
|
RB Linense | 28 | 10 | 11 | 7 | 40:28 | 12 | 41 |
| 8 |
|
UD Melilla | 28 | 11 | 8 | 9 | 27:19 | 8 | 41 |
| 9 |
|
CF Villanovense | 28 | 10 | 10 | 8 | 21:25 | -4 | 40 |
| 10 |
|
Écija Balompié | 28 | 9 | 9 | 10 | 30:42 | -12 | 36 |
| 11 |
|
CD Badajoz | 28 | 8 | 11 | 9 | 36:32 | 4 | 35 |
| 12 |
|
Recreativo Huelva | 28 | 9 | 8 | 11 | 26:27 | -1 | 35 |
| 13 |
|
San Fernando CD | 28 | 8 | 10 | 10 | 31:32 | -1 | 34 |
| 14 |
|
CD El Ejido 2012 | 28 | 8 | 10 | 10 | 40:42 | -2 | 34 |
| 15 |
|
Mérida AD | 28 | 8 | 10 | 10 | 27:31 | -4 | 34 |
| 16 |
|
UD Las Palmas B | 28 | 8 | 7 | 13 | 30:35 | -5 | 31 |
| 17 |
|
Córdoba CF B | 28 | 7 | 9 | 12 | 33:37 | -4 | 30 |
| 18 |
|
FC Jumilla | 28 | 6 | 11 | 11 | 20:33 | -13 | 29 |
| 19 |
|
Real Betis B | 28 | 6 | 9 | 13 | 34:48 | -14 | 27 |
| 20 |
|
Lorca Deportiva | 28 | 7 | 6 | 15 | 25:48 | -23 | 27 |
| Playoffs | |
| Playoffs | |
| Relegation | |
| Abstieg |
