 |
 |
|
| 23.01.2022 | 11:00 | Mérida AD | - | CF Panadería Pulido | 2:1 (0:1) | |
| 12:00 | CD San Roque | - | Cádiz CF B | 0:0 (0:0) | ||
| 12:00 | CF Villanovense | - | AD Ceuta FC | 0:1 (0:0) | ||
| 12:30 | CD Mensajero | - | Don Benito | 1:2 (0:1) | ||
| 13:00 | UD Las Palmas B | - | UD Montijo | 0:3 (0:1) | ||
| 17:00 | Antequera CF | - | CD Coria | 0:0 (0:0) | ||
| 17:00 | Córdoba CF | - | Xerez DFC | 4:0 (2:0) | ||
| 02.02.2022 | 20:30 | CP Cacereño | - | Vélez CF | 2:0 (2:0) | |
| 16.03.2022 | 21:00 | UD San Fernando | - | UD Tamaraceite | 3:2 (3:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Córdoba CF | 18 | 13 | 4 | 1 | 48:12 | 36 | 43 |
| 2 |
|
CP Cacereño | 18 | 10 | 6 | 2 | 25:16 | 9 | 36 |
| 3 |
|
CD Coria | 18 | 9 | 5 | 4 | 20:15 | 5 | 32 |
| 4 |
|
AD Ceuta FC | 18 | 8 | 7 | 3 | 22:15 | 7 | 31 |
| 5 |
|
CF Villanovense | 18 | 9 | 4 | 5 | 22:13 | 9 | 31 |
| 6 |
|
UD Montijo | 18 | 9 | 2 | 7 | 21:17 | 4 | 29 |
| 7 |
|
Mérida AD | 18 | 7 | 5 | 6 | 22:16 | 6 | 26 |
| 8 |
|
Vélez CF | 18 | 8 | 2 | 8 | 25:21 | 4 | 26 |
| 9 |
|
CD San Roque | 18 | 6 | 7 | 5 | 19:14 | 5 | 25 |
| 10 |
|
Don Benito | 18 | 6 | 6 | 6 | 28:22 | 6 | 24 |
| 11 |
|
Cádiz CF B | 18 | 5 | 7 | 6 | 15:20 | -5 | 22 |
| 12 |
|
Antequera CF | 18 | 5 | 6 | 7 | 17:23 | -6 | 21 |
| 13 |
|
Xerez DFC | 18 | 6 | 3 | 9 | 16:29 | -13 | 21 |
| 14 |
|
UD Las Palmas B | 18 | 4 | 7 | 7 | 19:27 | -8 | 19 |
| 15 |
|
CD Mensajero | 18 | 3 | 9 | 6 | 18:26 | -8 | 18 |
| 16 |
|
UD San Fernando | 18 | 3 | 5 | 10 | 14:25 | -11 | 14 |
| 17 |
|
UD Tamaraceite | 18 | 3 | 4 | 11 | 16:32 | -16 | 13 |
| 18 |
|
CF Panadería Pulido | 18 | 1 | 5 | 12 | 12:36 | -24 | 8 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
