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| 05.03.2023 | 12:00 | Cádiz CF B | - | Xerez DFC | 3:0 (3:0) | |
| 12:00 | FC Cartagena B | - | Utrera CD | 3:2 (1:0) | ||
| 12:00 | Recreativo Granada | - | Mar Menor CF | 0:2 (0:1) | ||
| 12:30 | Real Betis B | - | Juventud Torremolinos | 2:1 (2:0) | ||
| 17:00 | Antequera CF | - | Sevilla Atlético | 0:2 (0:2) | ||
| 17:00 | CD El Ejido 2012 | - | Recreativo Huelva | 0:0 (0:0) | ||
| 17:00 | CD San Roque | - | Atlético Mancha Real | 0:2 (0:2) | ||
| 17:00 | Atlético Sanluqueño CF | - | Vélez CF | 2:0 (0:0) | ||
| 17:00 | Yeclano Deportivo | - | UCAM Murcia CF | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Antequera CF | 24 | 18 | 4 | 2 | 46:17 | 29 | 58 |
| 2 |
|
Recreativo Huelva | 24 | 11 | 8 | 5 | 26:19 | 7 | 41 |
| 3 |
|
Yeclano Deportivo | 24 | 10 | 9 | 5 | 25:19 | 6 | 39 |
| 4 |
|
UCAM Murcia CF | 24 | 9 | 10 | 5 | 34:23 | 11 | 37 |
| 5 |
|
Atlético Sanluqueño CF | 24 | 10 | 7 | 7 | 31:25 | 6 | 37 |
| 6 |
|
Recreativo Granada | 24 | 10 | 6 | 8 | 32:26 | 6 | 36 |
| 7 |
|
Real Betis B | 24 | 9 | 8 | 7 | 23:22 | 1 | 35 |
| 8 |
|
Mar Menor CF | 24 | 9 | 8 | 7 | 26:22 | 4 | 35 |
| 9 |
|
CD San Roque | 24 | 9 | 6 | 9 | 25:23 | 2 | 33 |
| 10 |
|
FC Cartagena B | 24 | 9 | 5 | 10 | 26:31 | -5 | 32 |
| 11 |
|
Vélez CF | 24 | 9 | 3 | 12 | 24:34 | -10 | 30 |
| 12 |
|
CD El Ejido 2012 | 24 | 8 | 5 | 11 | 25:27 | -2 | 29 |
| 13 |
|
Atlético Mancha Real | 24 | 8 | 5 | 11 | 19:30 | -11 | 29 |
| 14 |
|
Cádiz CF B | 24 | 7 | 7 | 10 | 26:30 | -4 | 28 |
| 15 |
|
Xerez DFC | 24 | 6 | 7 | 11 | 20:28 | -8 | 25 |
| 16 |
|
Juventud Torremolinos | 24 | 5 | 9 | 10 | 20:24 | -4 | 24 |
| 17 |
|
Sevilla Atlético | 24 | 7 | 3 | 14 | 22:26 | -4 | 24 |
| 18 |
|
Utrera CD | 24 | 5 | 4 | 15 | 20:44 | -24 | 19 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
