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| H | UAG Tecos | - | CF Monterrey | 0:3 (0:1) | ||
| R | CF Monterrey | - | UAG Tecos | 4:0 (1:0) | ||
| H: 01.12.2005 02:00 | R: 04.12.2005 00:00 | Sieger: CF Monterrey | ||||
| H | CF Pachuca | - | Club Necaxa | 2:0 (2:0) | ||
| R | Club Necaxa | - | CF Pachuca | 0:2 (0:1) | ||
| H: 01.12.2005 04:00 | R: 04.12.2005 03:30 | Sieger: CF Pachuca | ||||
| H | Deportivo Toluca | - | Cruz Azul | 1:0 (0:0) | ||
| R | Cruz Azul | - | Deportivo Toluca | 0:0 (0:0) | ||
| H: 01.12.2005 22:00 | R: 05.12.2005 03:00 | Sieger: Deportivo Toluca | ||||
| H | UANL Tigres | - | CF América | 1:3 (0:1) | ||
| R | CF América | - | UANL Tigres | 1:4 (0:3) | ||
| H: 02.12.2005 03:45 | R: 05.12.2005 00:00 | Sieger: UANL Tigres | ||||
