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| H | CF Pachuca | - | Deportivo Toluca | 2:2 (0:0) | ||
| R | Deportivo Toluca | - | CF Pachuca | 1:0 (1:0) | ||
| H: 13.05.2010 02:00 | R: 16.05.2010 03:00 | Sieger: Deportivo Toluca | ||||
| H | Monarcas Morelia | - | Santos Laguna | 3:3 (1:1) | ||
| R | Santos Laguna | - | Monarcas Morelia | 7:1 (3:1) | ||
| H: 13.05.2010 04:00 | R: 16.05.2010 01:00 | Sieger: Santos Laguna | ||||
