 |
 |
|
|
| 17.12.2021 | 17:00 | FC DAC 1904 | - | MFK Ružomberok | 0:0 (0:0) | |
| 18.12.2021 | 15:00 | FK Senica | - | AS Trenčín | 1:0 (1:0) | |
| 15:00 | Zlaté Moravce | - | MFK Zemplín Michalovce | 0:1 (0:0) | ||
| 15:00 | FK Pohronie | - | Tatran Liptovský Mikuláš | 2:2 (0:1) | ||
| 15:00 | ŠKF Sereď | - | Spartak Trnava | 0:1 (0:1) | ||
| 19.12.2021 | 17:00 | MŠK Žilina | - | Slovan Bratislava | 1:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slovan Bratislava | 19 | 14 | 4 | 1 | 43:13 | 30 | 46 |
| 2 |
|
Spartak Trnava | 19 | 13 | 3 | 3 | 28:11 | 17 | 42 |
| 3 |
|
MFK Ružomberok | 19 | 9 | 8 | 2 | 31:13 | 18 | 35 |
| 4 |
|
FC DAC 1904 | 19 | 9 | 5 | 5 | 24:19 | 5 | 32 |
| 5 |
|
MŠK Žilina | 19 | 7 | 6 | 6 | 30:24 | 6 | 27 |
| 6 |
|
FK Senica | 19 | 6 | 6 | 7 | 19:25 | -6 | 24 |
| 7 |
|
ŠKF Sereď | 19 | 6 | 5 | 8 | 23:26 | -3 | 23 |
| 8 |
|
MFK Zemplín Michalovce | 19 | 7 | 2 | 10 | 19:27 | -8 | 23 |
| 9 |
|
AS Trenčín | 19 | 5 | 5 | 9 | 27:31 | -4 | 20 |
| 10 |
|
Tatran Liptovský Mikuláš | 19 | 4 | 4 | 11 | 22:39 | -17 | 16 |
| 11 |
|
Zlaté Moravce | 19 | 3 | 6 | 10 | 19:34 | -15 | 15 |
| 12 |
|
FK Pohronie | 19 | 2 | 4 | 13 | 16:39 | -23 | 10 |
| Playoffs | |
| Relegation |
