| 1. Runde | 22.01.2020 | Club San José | - | Guaraní | 0:1 | ||||
| 1. Runde | 29.01.2020 | Guaraní | - | Club San José | 4:0 | ||||
| 2. Runde | 06.02.2020 | Guaraní | - | Corinthians SP | 1:0 | ||||
| 2. Runde | 13.02.2020 | Corinthians SP | - | Guaraní | 2:1 | ||||
| 3. Runde | 20.02.2020 | Palestino | - | Guaraní | 0:1 | ||||
| 3. Runde | 27.02.2020 | Guaraní | - | Palestino | 2:1 | ||||
| Gruppe 2 | 18.09.2020 | Guaraní | - | Tigre | 4:1 | ||||
| Gruppe 2 | 24.09.2020 | Guaraní | - | Palmeiras | 0:0 | ||||
| Gruppe 2 | 02.10.2020 | Tigre | - | Guaraní | 1:3 |  |
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| Gruppe 2 | 22.10.2020 | Bolívar | - | Guaraní | 2:3 | |
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| Achtelfinale | 27.11.2020 | Guaraní | - | Grêmio Porto Alegre | 0:2 | ||||
| Achtelfinale | 04.12.2020 | Grêmio Porto Alegre | - | Guaraní | 2:0 | |
Paraguay