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| 05.03.2022 | 17:00 | EA Guingamp (CFA) | - | St-Pryvé St-Hilaire | 1:1 (1:0) | |
| 17:00 | FC Lorient (CFA) | - | Blois Foot 41 | 0:1 (0:0) | ||
| 18:00 | AS Poissy | - | Stade Plabennec | 3:2 (0:2) | ||
| 18:00 | C'Chartres Football | - | US Saint-Malo | 2:1 (1:0) | ||
| 18:00 | US Granvillaise | - | FC Rouen 1899 | 0:0 (0:0) | ||
| 18:00 | SO Romorantin | - | SM Caen (CFA) | 0:1 (0:0) | ||
| 18:00 | Châteaubriant Voltigeurs | - | FC Versailles | 0:3 (0:1) | ||
| 18:30 | Vannes OC | - | AS Vitré | 3:1 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Versailles | 20 | 11 | 8 | 1 | 31:12 | 19 | 41 |
| 2 |
|
C'Chartres Football | 20 | 11 | 3 | 6 | 35:23 | 12 | 36 |
| 3 |
|
FC Lorient (CFA) | 20 | 10 | 5 | 5 | 26:15 | 11 | 35 |
| 4 |
|
Vannes OC | 20 | 9 | 6 | 5 | 31:23 | 8 | 33 |
| 5 |
|
Blois Foot 41 | 20 | 9 | 6 | 5 | 29:31 | -2 | 33 |
| 6 |
|
St-Pryvé St-Hilaire | 20 | 9 | 5 | 6 | 25:20 | 5 | 32 |
| 7 |
|
SM Caen (CFA) | 20 | 8 | 6 | 6 | 23:24 | -1 | 30 |
| 8 |
|
Châteaubriant Voltigeurs | 20 | 8 | 4 | 8 | 23:24 | -1 | 28 |
| 9 |
|
EA Guingamp (CFA) | 20 | 6 | 7 | 7 | 23:29 | -6 | 25 |
| 10 |
|
FC Rouen 1899 | 20 | 5 | 8 | 7 | 19:20 | -1 | 23 |
| 11 |
|
US Granvillaise | 20 | 4 | 11 | 5 | 19:19 | 0 | 23 |
| 12 |
|
AS Poissy | 20 | 4 | 10 | 6 | 21:24 | -3 | 22 |
| 13 |
|
US Saint-Malo | 20 | 5 | 5 | 10 | 14:23 | -9 | 20 |
| 14 |
|
SO Romorantin | 20 | 5 | 4 | 11 | 17:30 | -13 | 19 |
| 15 |
|
AS Vitré | 20 | 4 | 5 | 11 | 21:29 | -8 | 17 |
| 16 |
|
Stade Plabennec | 20 | 3 | 5 | 12 | 17:28 | -11 | 14 |
| Aufstieg | |
| Abstieg |
