| 1. Runde | 02.10.2008 | AS Saint-Étienne | - | Hapoel Tel Aviv | 2:1 | ||||
| Gruppe G | 23.10.2008 | FC København | - | AS Saint-Étienne | 1:3 | ||||
| Gruppe G | 06.11.2008 | AS Saint-Étienne | - | Rosenborg BK | 3:0 |  |
 |
||
| Gruppe G | 27.11.2008 | Club Brugge KV | - | AS Saint-Étienne | 1:1 | ||||
| Gruppe G | 17.12.2008 | AS Saint-Étienne | - | Valencia CF | 2:2 | ||||
| 3. Runde | 18.02.2009 | Olympiakos Piraeus | - | AS Saint-Étienne | 1:3 | ||||
| 3. Runde | 26.02.2009 | AS Saint-Étienne | - | Olympiakos Piraeus | 2:1 | ||||
| Achtelfinale | 12.03.2009 | Werder Bremen | - | AS Saint-Étienne | 1:0 |
Portugal