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| H | UE Lleida | - | Palamós CF | 0:0 | ||
| R | Palamós CF | - | UE Lleida | 3:4 i.E. | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: UE Lleida | ||||
| H | Real Jaén | - | UE Figueres | 2:1 | ||
| R | UE Figueres | - | Real Jaén | 4:5 i.E. | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: Real Jaén | ||||
| H | CF Extremadura | - | CE Sabadell | 2:1 | ||
| R | CE Sabadell | - | CF Extremadura | 0:0 | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: CF Extremadura | ||||
| H | FC Cartagena | - | Real Valladolid | 1:2 | ||
| R | Real Valladolid | - | FC Cartagena | 4:1 | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: Real Valladolid | ||||
| H | RCD Mallorca | - | CD Tenerife | 1:3 | ||
| R | CD Tenerife | - | RCD Mallorca | 5:6 i.E. | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: RCD Mallorca | ||||
| H | Villarreal CF | - | SD Compostela | 0:0 | ||
| R | SD Compostela | - | Villarreal CF | 0:1 | ||
| H: 13.01.1993 | R: 21.01.1993 | Sieger: Villarreal CF | ||||
| H | Sporting Gijón | - | CA Osasuna | 4:1 | ||
| R | CA Osasuna | - | Sporting Gijón | 2:0 | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: Sporting Gijón | ||||
| H | CP Mérida | - | Sevilla FC | 0:1 | ||
| R | Sevilla FC | - | CP Mérida | 1:1 | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: Sevilla FC | ||||
| H | Real Betis | - | Real Oviedo | 2:1 | ||
| R | Real Oviedo | - | Real Betis | 5:0 | ||
| H: 13.01.1993 | R: 20.01.1993 | Sieger: Real Oviedo | ||||
| H | CD Lugo | - | Albacete | 0:3 | ||
| R | Albacete | - | CD Lugo | 0:0 | ||
| H: 20.01.1993 | R: 28.01.1993 | Sieger: Albacete | ||||
