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| 29.01.2000 | 20:00 | SBV Eindhoven | - | BV Emmen | 0:1 (0:0) | |
| 20:00 | SBV Excelsior | - | FC Groningen | 1:0 (0:0) | ||
| 20:00 | HFC Haarlem | - | Dordrecht '90 | 2:4 (1:2) | ||
| 20:00 | Helmond Sport | - | FC Volendam | 2:1 (0:1) | ||
| 20:00 | ADO Den Haag | - | Telstar | 1:4 (0:1) | ||
| 20:00 | TOP Oss | - | VVV | 2:4 (1:2) | ||
| 20:00 | BV Veendam | - | NAC Breda | 0:2 (0:1) | ||
| 20:00 | FC Zwolle | - | Heracles Almelo | 1:0 (0:0) | ||
| 02.02.2000 | 20:00 | RBC Roosendaal | - | Go Ahead Eagles | 1:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Zwolle | 19 | 13 | 4 | 2 | 54:23 | 31 | 43 |
| 2 |
|
NAC Breda | 19 | 14 | 1 | 4 | 48:20 | 28 | 43 |
| 3 |
|
FC Groningen | 19 | 12 | 4 | 3 | 46:18 | 28 | 40 |
| 4 |
|
BV Emmen | 19 | 10 | 4 | 5 | 30:24 | 6 | 34 |
| 5 |
|
RBC Roosendaal | 19 | 9 | 4 | 6 | 35:25 | 10 | 31 |
| 6 |
|
SBV Excelsior | 19 | 9 | 3 | 7 | 36:27 | 9 | 30 |
| 7 |
|
Dordrecht '90 | 19 | 8 | 4 | 7 | 37:33 | 4 | 28 |
| 8 |
|
ADO Den Haag | 19 | 8 | 3 | 8 | 22:30 | -8 | 27 |
| 9 |
|
Heracles Almelo | 19 | 7 | 4 | 8 | 23:23 | 0 | 25 |
| 10 |
|
Telstar | 19 | 8 | 1 | 10 | 25:35 | -10 | 25 |
| 11 |
|
Go Ahead Eagles | 19 | 6 | 4 | 9 | 36:34 | 2 | 22 |
| 12 |
|
VVV | 19 | 5 | 6 | 8 | 26:37 | -11 | 21 |
| 13 |
|
BV Veendam | 19 | 5 | 6 | 8 | 28:40 | -12 | 21 |
| 14 |
|
SBV Eindhoven | 19 | 6 | 3 | 10 | 20:38 | -18 | 21 |
| 15 |
|
FC Volendam | 19 | 5 | 5 | 9 | 24:38 | -14 | 20 |
| 16 |
|
Helmond Sport | 19 | 6 | 1 | 12 | 22:37 | -15 | 19 |
| 17 |
|
HFC Haarlem | 19 | 5 | 2 | 12 | 31:43 | -12 | 17 |
| 18 |
|
TOP Oss | 19 | 4 | 3 | 12 | 16:34 | -18 | 15 |
