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| 16.09.2005 | 20:00 | BV Veendam | - | FC Dordrecht | 2:0 (1:0) | |
| 20:00 | SBV Excelsior | - | MVV | 1:0 (1:0) | ||
| 20:00 | FC Den Bosch | - | De Graafschap | 2:0 (0:0) | ||
| 20:00 | FC Eindhoven | - | FC Volendam | 1:2 (1:2) | ||
| 20:00 | Go Ahead Eagles | - | HFC Haarlem | 3:0 (0:0) | ||
| 20:00 | Stormvogels Telstar | - | FC Zwolle | 1:3 (0:1) | ||
| 20:00 | VVV-Venlo | - | TOP Oss | 2:0 (0:0) | ||
| 20:00 | SC Cambuur | - | Helmond Sport | 0:0 (0:0) | ||
| 20:00 | Fortuna Sittard | - | FC Omniworld | 2:3 (0:0) | ||
| 20:00 | AGOVV | - | FC Emmen | 2:3 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VVV-Venlo | 8 | 7 | 1 | 0 | 17:3 | 14 | 22 |
| 2 |
|
FC Volendam | 8 | 6 | 2 | 0 | 16:4 | 12 | 20 |
| 3 |
|
SBV Excelsior | 8 | 6 | 2 | 0 | 13:5 | 8 | 20 |
| 4 |
|
FC Emmen | 8 | 5 | 1 | 2 | 17:11 | 6 | 16 |
| 5 |
|
FC Den Bosch | 8 | 5 | 1 | 2 | 14:9 | 5 | 16 |
| 6 |
|
Helmond Sport | 8 | 4 | 2 | 2 | 15:8 | 7 | 14 |
| 7 |
|
FC Zwolle | 8 | 3 | 3 | 2 | 13:12 | 1 | 12 |
| 8 |
|
MVV | 8 | 3 | 2 | 3 | 12:10 | 2 | 11 |
| 9 |
|
FC Dordrecht | 8 | 3 | 2 | 3 | 10:11 | -1 | 11 |
| 10 |
|
FC Eindhoven | 8 | 3 | 1 | 4 | 16:10 | 6 | 10 |
| 11 |
|
AGOVV | 8 | 3 | 1 | 4 | 12:14 | -2 | 10 |
| 12 |
|
De Graafschap | 8 | 3 | 1 | 4 | 7:10 | -3 | 10 |
| 13 |
|
BV Veendam | 8 | 2 | 2 | 4 | 8:10 | -2 | 8 |
| 14 |
|
Go Ahead Eagles | 8 | 1 | 4 | 3 | 13:17 | -4 | 7 |
| 15 |
|
HFC Haarlem | 8 | 2 | 1 | 5 | 8:18 | -10 | 7 |
| 16 |
|
Stormvogels Telstar | 8 | 1 | 3 | 4 | 8:13 | -5 | 6 |
| 17 |
|
TOP Oss | 8 | 1 | 3 | 4 | 5:12 | -7 | 6 |
| 18 |
|
Fortuna Sittard | 8 | 1 | 2 | 5 | 9:19 | -10 | 5 |
| 19 |
|
FC Omniworld | 8 | 1 | 1 | 6 | 9:20 | -11 | 4 |
| 20 |
|
SC Cambuur | 8 | 0 | 5 | 3 | 7:13 | -6 | 2 |
| Aufstieg |
|
# Cambuur-Leeuwarden bekam 3 Punkte abgezogen. |
