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| 21.12.1941 | Arenas de Getxo | - | UD Salamanca | 2:3 | ||
| Real Valladolid | - | Barakaldo CF | 3:1 | |||
| Racing Ferrol | - | Racing Santander | 5:0 | |||
| Real Unión | - | Sporting Gijón | 1:0 | |||
| CA Osasuna | - | AD Ferroviaria | 2:0 | |||
| CD Alavés | - | CD Constància | 2:2 | |||
| Girona FC | - | Real Zaragoza | 3:2 | |||
| Levante UD | - | CE Sabadell | 1:1 | |||
| CD Málacitano | - | UD Cartagena | 1:3 | |||
| Real Murcia | - | Real Betis | 2:3 | |||
| AD Ceuta | - | Elche CF | 3:0 | |||
| Xerez FC | - | Cádiz CF | 2:3 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Real Betis | 13 | 7 | 4 | 2 | 37:21 | 16 | 18:8 |
| 2 |
|
Sporting Gijón | 13 | 7 | 4 | 2 | 35:22 | 13 | 18:8 |
| 3 |
|
Real Murcia | 13 | 8 | 1 | 4 | 36:24 | 12 | 17:9 |
| 4 |
|
CE Sabadell | 13 | 5 | 7 | 1 | 24:13 | 11 | 17:9 |
| 5 |
|
CD Alavés | 13 | 7 | 2 | 4 | 29:23 | 6 | 16:10 |
| 6 |
|
UD Salamanca | 13 | 8 | 0 | 5 | 26:25 | 1 | 16:10 |
| 7 |
|
Racing Ferrol | 13 | 6 | 3 | 4 | 30:17 | 13 | 15:11 |
| 8 |
|
Girona FC | 13 | 6 | 3 | 4 | 24:19 | 5 | 15:11 |
| 9 |
|
Real Valladolid | 13 | 6 | 2 | 5 | 31:19 | 12 | 14:12 |
| 10 |
|
AD Ceuta | 13 | 5 | 4 | 4 | 26:17 | 9 | 14:12 |
| 11 |
|
Cádiz CF | 13 | 6 | 2 | 5 | 26:18 | 8 | 14:12 |
| 12 |
|
Barakaldo CF | 13 | 6 | 2 | 5 | 29:25 | 4 | 14:12 |
| 13 |
|
Real Zaragoza | 13 | 5 | 4 | 4 | 25:23 | 2 | 14:12 |
| 14 |
|
CD Málacitano | 13 | 5 | 4 | 4 | 19:18 | 1 | 14:12 |
| 15 |
|
CA Osasuna | 13 | 5 | 3 | 5 | 29:22 | 7 | 13:13 |
| 16 |
|
CD Constància | 13 | 4 | 5 | 4 | 22:17 | 5 | 13:13 |
| 17 |
|
Racing Santander | 13 | 4 | 5 | 4 | 23:24 | -1 | 13:13 |
| 18 |
|
AD Ferroviaria | 13 | 4 | 2 | 7 | 17:23 | -6 | 10:16 |
| 19 |
|
Arenas de Getxo | 13 | 5 | 0 | 8 | 22:35 | -13 | 10:16 |
| 20 |
|
Xerez FC | 13 | 3 | 3 | 7 | 23:34 | -11 | 9:17 |
| 21 |
|
Elche CF | 13 | 3 | 3 | 7 | 20:35 | -15 | 9:17 |
| 22 |
|
UD Cartagena | 13 | 3 | 3 | 7 | 17:37 | -20 | 9:17 |
| 23 |
|
Levante UD | 13 | 2 | 2 | 9 | 16:46 | -30 | 6:20 |
| 24 |
|
Real Unión | 13 | 1 | 2 | 10 | 16:45 | -29 | 4:22 |
