 |
 |
|
|
| 29.01.2022 | 14:00 | Lamia | - | OFI Heraklion | 2:1 (0:1) | |
| 14:00 | Panathinaikos | - | Asteras Tripolis | 0:1 (0:0) | ||
| 16:15 | Ionikos Nikea | - | Atromitos | 2:1 (2:0) | ||
| 30.01.2022 | 14:00 | Panetolikos | - | Aris Saloniki | 0:2 (0:2) | |
| 14:00 | PAS Giannina | - | Apollon Smyrnis | 2:0 (1:0) | ||
| 16:15 | AEK Athen | - | Volos NFC | 1:2 (1:1) | ||
| 18:30 | PAOK Saloniki | - | Olympiakos Piraeus | 1:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Olympiakos Piraeus | 20 | 15 | 5 | 0 | 36:11 | 25 | 50 |
| 2 |
|
PAOK Saloniki | 20 | 12 | 3 | 5 | 42:22 | 20 | 39 |
| 3 |
|
AEK Athen | 20 | 11 | 4 | 5 | 34:21 | 13 | 37 |
| 4 |
|
Aris Saloniki | 20 | 10 | 5 | 5 | 22:15 | 7 | 35 |
| 5 |
|
Panathinaikos | 20 | 10 | 3 | 7 | 31:15 | 16 | 33 |
| 6 |
|
PAS Giannina | 20 | 8 | 6 | 6 | 24:20 | 4 | 30 |
| 7 |
|
Asteras Tripolis | 20 | 8 | 5 | 7 | 20:20 | 0 | 29 |
| 8 |
|
OFI Heraklion | 20 | 6 | 8 | 6 | 24:25 | -1 | 26 |
| 9 |
|
Volos NFC | 20 | 7 | 3 | 10 | 31:38 | -7 | 24 |
| 10 |
|
Panetolikos | 20 | 7 | 3 | 10 | 23:34 | -11 | 24 |
| 11 |
|
Ionikos Nikea | 20 | 5 | 5 | 10 | 20:25 | -5 | 20 |
| 12 |
|
Lamia | 20 | 4 | 6 | 10 | 17:25 | -8 | 18 |
| 13 |
|
Atromitos | 20 | 3 | 4 | 13 | 18:41 | -23 | 13 |
| 14 |
|
Apollon Smyrnis | 20 | 1 | 6 | 13 | 7:37 | -30 | 9 |
| Playoffs | |
| Relegation |
