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| 11.03.2006 | 18:30 | CD Numancia | - | CD Tenerife | 2:0 (0:0) | |
| 18:30 | CD Castellón | - | Sporting Gijón | 1:0 (1:0) | ||
| 18:30 | UD Almería | - | Real Valladolid | 2:1 (0:0) | ||
| 18:30 | Real Madrid Castilla | - | SD Eibar | 1:0 (1:0) | ||
| 18:30 | Atlético Malagueño | - | Lorca Deportiva | 2:1 (1:1) | ||
| 19:00 | Hércules CF | - | UE Lleida | 2:1 (2:1) | ||
| 12.03.2006 | 12:00 | Recreativo Huelva | - | Levante UD | 4:1 (2:1) | |
| 17:00 | Gimnàstic de Tarragona | - | Polideportivo Ejido | 2:0 (1:0) | ||
| 17:00 | Albacete | - | Racing Ferrol | 1:2 (0:1) | ||
| 17:00 | Real Murcia | - | Elche CF | 1:0 (0:0) | ||
| 17:30 | Xerez CD | - | Ciudad de Murcia | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Recreativo Huelva | 28 | 14 | 9 | 5 | 40:23 | 17 | 51 |
| 2 |
|
Xerez CD | 28 | 13 | 10 | 5 | 44:27 | 17 | 49 |
| 3 |
|
Gimnàstic de Tarragona | 28 | 15 | 4 | 9 | 31:26 | 5 | 49 |
| 4 |
|
Lorca Deportiva | 28 | 13 | 7 | 8 | 39:26 | 13 | 46 |
| 5 |
|
Levante UD | 28 | 12 | 10 | 6 | 37:30 | 7 | 46 |
| 6 |
|
UD Almería | 28 | 13 | 6 | 9 | 34:25 | 9 | 45 |
| 7 |
|
CD Numancia | 28 | 11 | 9 | 8 | 28:32 | -4 | 42 |
| 8 |
|
Real Madrid Castilla | 28 | 11 | 6 | 11 | 36:30 | 6 | 39 |
| 9 |
|
Ciudad de Murcia | 28 | 10 | 9 | 9 | 31:31 | 0 | 39 |
| 10 |
|
Real Valladolid | 28 | 9 | 11 | 8 | 37:33 | 4 | 38 |
| 11 |
|
Real Murcia | 28 | 9 | 10 | 9 | 26:25 | 1 | 37 |
| 12 |
|
Albacete | 28 | 10 | 7 | 11 | 28:37 | -9 | 37 |
| 13 |
|
Sporting Gijón | 28 | 8 | 12 | 8 | 27:23 | 4 | 36 |
| 14 |
|
Elche CF | 28 | 9 | 8 | 11 | 32:38 | -6 | 35 |
| 15 |
|
UE Lleida | 28 | 9 | 6 | 13 | 27:29 | -2 | 33 |
| 16 |
|
Polideportivo Ejido | 28 | 9 | 6 | 13 | 29:35 | -6 | 33 |
| 17 |
|
Hércules CF | 28 | 8 | 9 | 11 | 28:35 | -7 | 33 |
| 18 |
|
CD Tenerife | 28 | 8 | 7 | 13 | 33:42 | -9 | 31 |
| 19 |
|
Racing Ferrol | 28 | 6 | 12 | 10 | 33:39 | -6 | 30 |
| 20 |
|
CD Castellón | 28 | 7 | 8 | 13 | 26:36 | -10 | 29 |
| 21 |
|
Atlético Malagueño | 28 | 6 | 9 | 13 | 22:35 | -13 | 27 |
| 22 |
|
SD Eibar | 28 | 4 | 13 | 11 | 19:30 | -11 | 25 |
