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| 15.10.1999 | FV Bad Vilbel | - | SV Bernbach | 5:0 | ||
| 16.10.1999 | SC Neukirchen | - | FSC Lohfelden | 2:1 | ||
| TGM SV Jügesheim | - | SG 01 Hoechst | 2:1 | |||
| SGV Germania Horbach | - | SVA Bad Hersfeld | 3:1 | |||
| VfB Unterliederbach | - | FSV Braunfels | 3:3 | |||
| KSV Baunatal | - | VfB Marburg | 1:4 | |||
| VfB Gießen | - | Eintracht Frankfurt II | 3:3 | |||
| 17.10.1999 | Kickers Offenbach II | - | KSV Klein-Karben | 0:0 | ||
| FC Ederbergland | - | Viktoria Aschaffenburg | 1:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FV Bad Vilbel | 13 | 7 | 5 | 1 | 27:14 | 13 | 26 |
| 2 |
|
SG 01 Hoechst | 13 | 8 | 2 | 3 | 27:16 | 11 | 26 |
| 3 |
|
SC Neukirchen | 13 | 8 | 2 | 3 | 25:15 | 10 | 26 |
| 4 |
|
SVA Bad Hersfeld | 13 | 6 | 3 | 4 | 27:22 | 5 | 21 |
| 5 |
|
FSC Lohfelden | 13 | 6 | 2 | 5 | 34:26 | 8 | 20 |
| 6 |
|
KSV Klein-Karben | 13 | 5 | 5 | 3 | 20:12 | 8 | 20 |
| 7 |
|
Viktoria Aschaffenburg | 13 | 4 | 6 | 3 | 17:13 | 4 | 18 |
| 8 |
|
KSV Baunatal | 13 | 5 | 3 | 5 | 18:21 | -3 | 18 |
| 9 |
|
TGM SV Jügesheim | 13 | 5 | 2 | 6 | 20:24 | -4 | 17 |
| 10 |
|
VfB Gießen | 13 | 3 | 7 | 3 | 24:22 | 2 | 16 |
| 11 |
|
VfB Marburg | 13 | 4 | 4 | 5 | 20:23 | -3 | 16 |
| 12 |
|
SV Bernbach | 13 | 5 | 1 | 7 | 19:25 | -6 | 16 |
| 13 |
|
Eintracht Frankfurt II | 13 | 4 | 3 | 6 | 19:21 | -2 | 15 |
| 14 |
|
FC Ederbergland | 13 | 3 | 5 | 5 | 18:19 | -1 | 14 |
| 15 |
|
Kickers Offenbach II | 13 | 3 | 5 | 5 | 21:30 | -9 | 14 |
| 16 |
|
SGV Germania Horbach | 13 | 3 | 4 | 6 | 13:25 | -12 | 13 |
| 17 |
|
VfB Unterliederbach | 13 | 3 | 3 | 7 | 24:31 | -7 | 12 |
| 18 |
|
FSV Braunfels | 13 | 1 | 6 | 6 | 15:29 | -14 | 9 |
