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| 13.11.1999 | SC Neukirchen | - | FV Bad Vilbel | 2:0 | ||
| SVA Bad Hersfeld | - | VfB Marburg | 2:2 | |||
| SGV Germania Horbach | - | Viktoria Aschaffenburg | 3:0 | |||
| Kickers Offenbach II | - | FSC Lohfelden | 1:1 | |||
| KSV Baunatal | - | SG 01 Hoechst | 3:3 | |||
| FC Ederbergland | - | SV Bernbach | 2:2 | |||
| VfB Gießen | - | TGM SV Jügesheim | 4:2 | |||
| 14.11.1999 | VfB Unterliederbach | - | Eintracht Frankfurt II | 1:3 | ||
| FSV Braunfels | - | KSV Klein-Karben | 3:4 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Neukirchen | 17 | 10 | 4 | 3 | 34:20 | 14 | 34 |
| 2 |
|
SG 01 Hoechst | 17 | 9 | 4 | 4 | 39:23 | 16 | 31 |
| 3 |
|
KSV Klein-Karben | 17 | 8 | 6 | 3 | 33:18 | 15 | 30 |
| 4 |
|
FSC Lohfelden | 17 | 9 | 3 | 5 | 43:30 | 13 | 30 |
| 5 |
|
FV Bad Vilbel | 17 | 8 | 6 | 3 | 29:17 | 12 | 30 |
| 6 |
|
Viktoria Aschaffenburg | 17 | 6 | 7 | 4 | 26:18 | 8 | 25 |
| 7 |
|
SVA Bad Hersfeld | 17 | 7 | 4 | 6 | 32:31 | 1 | 25 |
| 8 |
|
Eintracht Frankfurt II | 17 | 7 | 3 | 7 | 28:25 | 3 | 24 |
| 9 |
|
TGM SV Jügesheim | 17 | 7 | 3 | 7 | 28:31 | -3 | 24 |
| 10 |
|
KSV Baunatal | 17 | 6 | 5 | 6 | 26:28 | -2 | 23 |
| 11 |
|
SGV Germania Horbach | 17 | 6 | 5 | 6 | 21:27 | -6 | 23 |
| 12 |
|
VfB Gießen | 17 | 5 | 7 | 5 | 32:36 | -4 | 22 |
| 13 |
|
VfB Marburg | 17 | 5 | 6 | 6 | 25:28 | -3 | 21 |
| 14 |
|
FC Ederbergland | 17 | 4 | 6 | 7 | 22:25 | -3 | 18 |
| 15 |
|
SV Bernbach | 17 | 5 | 2 | 10 | 22:33 | -11 | 17 |
| 16 |
|
Kickers Offenbach II | 17 | 3 | 6 | 8 | 24:40 | -16 | 15 |
| 17 |
|
VfB Unterliederbach | 17 | 3 | 4 | 10 | 27:42 | -15 | 13 |
| 18 |
|
FSV Braunfels | 17 | 1 | 7 | 9 | 19:38 | -19 | 10 |
