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| 24.10.2021 | 15:00 | SV Breinig | - | SV 1914 Eilendorf | 3:3 (0:0) | |
| 15:00 | 1. FC Düren | - | FC Hürth | 5:2 (1:1) | ||
| 15:00 | BC Viktoria Glesch-Paffendorf | - | SV Bergisch Gladbach 09 | 0:1 (0:0) | ||
| 15:00 | VfL Alfter | - | Borussia Freialdenhoven | 3:1 (1:0) | ||
| 15:00 | Spvg Wesseling-Urfeld | - | Viktoria Arnoldsweiler | 2:0 (0:0) | ||
| 15:30 | FC Pesch 1956 | - | Blau-Weiß Friesdorf | 2:2 (0:1) | ||
| 15:30 | Fortuna Köln II | - | FC Hennef 05 | 1:2 (0:1) | ||
| 15:30 | SV Deutz 05 | - | SpVg Frechen 20 | 1:2 (0:0) | ||
| 15:30 | Siegburger SV 04 | - | VfL 08 Vichttal | 2:1 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Düren | 12 | 10 | 2 | 0 | 41:8 | 33 | 32 |
| 2 |
|
FC Hennef 05 | 12 | 9 | 2 | 1 | 29:7 | 22 | 29 |
| 3 |
|
SpVg Frechen 20 | 12 | 8 | 2 | 2 | 26:9 | 17 | 26 |
| 4 |
|
SV Bergisch Gladbach 09 | 12 | 7 | 4 | 1 | 32:7 | 25 | 25 |
| 5 |
|
Borussia Freialdenhoven | 12 | 7 | 1 | 4 | 21:14 | 7 | 22 |
| 6 |
|
Siegburger SV 04 | 12 | 6 | 4 | 2 | 17:11 | 6 | 22 |
| 7 |
|
VfL Alfter | 12 | 6 | 3 | 3 | 20:18 | 2 | 21 |
| 8 |
|
FC Hürth | 12 | 6 | 1 | 5 | 20:24 | -4 | 19 |
| 9 |
|
FC Pesch 1956 | 12 | 4 | 6 | 2 | 23:12 | 11 | 18 |
| 10 |
|
BC Viktoria Glesch-Paffendorf | 12 | 5 | 2 | 5 | 18:15 | 3 | 17 |
| 11 |
|
VfL 08 Vichttal | 12 | 5 | 2 | 5 | 20:22 | -2 | 17 |
| 12 |
|
Viktoria Arnoldsweiler | 12 | 5 | 1 | 6 | 21:21 | 0 | 16 |
| 13 |
|
Blau-Weiß Friesdorf | 12 | 3 | 4 | 5 | 17:23 | -6 | 13 |
| 14 |
|
Spvg Wesseling-Urfeld | 12 | 3 | 0 | 9 | 13:35 | -22 | 9 |
| 15 |
|
SV Deutz 05 | 12 | 2 | 2 | 8 | 12:30 | -18 | 8 |
| 16 |
|
Fortuna Köln II | 12 | 1 | 2 | 9 | 9:27 | -18 | 5 |
| 17 |
|
SV 1914 Eilendorf | 12 | 1 | 1 | 10 | 8:32 | -24 | 4 |
| 18 |
|
SV Breinig | 12 | 0 | 1 | 11 | 8:40 | -32 | 1 |
| Playoffs | |
| Abstieg |
