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| 01.04.2006 | 14:00 | FV Dresden-Nord | - | 1. FC Magdeburg | 4:1 | |
| 02.04.2006 | 13:30 | Sachsen Leipzig | - | VFC Plauen | 2:3 | |
| 14:00 | SV 1919 Grimma | - | FSV Budissa Bautzen | 1:2 | ||
| 14:00 | VfB Auerbach | - | FC Oberlausitz | 2:4 | ||
| 14:00 | ZFC Meuselwitz | - | VfB Pößneck | 2:1 | ||
| 14:00 | TSV Völpke | - | Hallescher FC | 1:3 | ||
| 14:00 | Germania Halberstadt | - | FC Eilenburg | 1:1 | ||
| 14:00 | Rot-Weiß Erfurt II | - | Energie Cottbus II | 0:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Magdeburg | 24 | 18 | 4 | 2 | 53:14 | 39 | 58 |
| 2 |
|
VFC Plauen | 24 | 16 | 3 | 5 | 43:30 | 13 | 51 |
| 3 |
|
Sachsen Leipzig | 24 | 14 | 4 | 6 | 37:16 | 21 | 46 |
| 4 |
|
Germania Halberstadt | 24 | 13 | 5 | 6 | 53:34 | 19 | 44 |
| 5 |
|
ZFC Meuselwitz | 24 | 12 | 7 | 5 | 41:31 | 10 | 43 |
| 6 |
|
Hallescher FC | 24 | 11 | 8 | 5 | 40:26 | 14 | 41 |
| 7 |
|
FSV Budissa Bautzen | 24 | 10 | 7 | 7 | 41:27 | 14 | 37 |
| 8 |
|
Rot-Weiß Erfurt II | 24 | 9 | 5 | 10 | 28:28 | 0 | 32 |
| 9 |
|
VfB Auerbach | 24 | 9 | 4 | 11 | 36:36 | 0 | 31 |
| 10 |
|
FC Eilenburg | 24 | 6 | 10 | 8 | 29:28 | 1 | 28 |
| 11 |
|
Energie Cottbus II | 24 | 7 | 7 | 10 | 33:37 | -4 | 28 |
| 12 |
|
FV Dresden-Nord | 24 | 5 | 11 | 8 | 32:34 | -2 | 26 |
| 13 |
|
SV 1919 Grimma | 24 | 4 | 6 | 14 | 26:43 | -17 | 18 |
| 14 |
|
VfB Pößneck | 24 | 5 | 3 | 16 | 22:45 | -23 | 18 |
| 15 |
|
TSV Völpke | 24 | 4 | 5 | 15 | 19:61 | -42 | 17 |
| 16 |
|
FC Oberlausitz | 24 | 4 | 1 | 19 | 26:69 | -43 | 13 |
