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| 20.05.2006 | 15:00 | SC Waldgirmes | - | FV Bad Vilbel | 4:1 | |
| 15:00 | Hessen Kassel | - | FSV Steinbach | 2:2 | ||
| 15:00 | KSV Baunatal | - | OSC Vellmar | 2:0 | ||
| 15:00 | SV Erzhausen | - | Bayern Alzenau | 0:1 | ||
| 15:00 | TSG Wörsdorf | - | Germania Ober-Roden | 3:1 | ||
| 15:00 | Viktoria Aschaffenburg | - | TSG Wattenbach | 4:1 | ||
| 15:00 | SV Buchonia Flieden | - | 1. FC Schwalmstadt | 3:6 | ||
| 15:00 | KSV Klein-Karben | - | FSV Frankfurt | 2:3 | ||
| 15:00 | Eintracht Frankfurt II | - | SG Bruchköbel | 3:2 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FSV Frankfurt | 33 | 23 | 6 | 4 | 73:25 | 48 | 75 |
| 2 |
|
Hessen Kassel | 33 | 22 | 6 | 5 | 74:25 | 49 | 72 |
| 3 |
|
SC Waldgirmes | 33 | 18 | 8 | 7 | 57:37 | 20 | 62 |
| 4 |
|
SV Buchonia Flieden | 33 | 16 | 7 | 10 | 48:38 | 10 | 55 |
| 5 |
|
Bayern Alzenau | 33 | 15 | 9 | 9 | 48:42 | 6 | 54 |
| 6 |
|
FV Bad Vilbel | 33 | 14 | 8 | 11 | 54:48 | 6 | 50 |
| 7 |
|
OSC Vellmar | 33 | 15 | 3 | 15 | 55:54 | 1 | 48 |
| 8 |
|
TSG Wörsdorf | 33 | 12 | 9 | 12 | 43:39 | 4 | 45 |
| 9 |
|
KSV Klein-Karben | 33 | 13 | 6 | 14 | 46:45 | 1 | 45 |
| 10 |
|
1. FC Schwalmstadt | 33 | 12 | 5 | 16 | 51:59 | -8 | 41 |
| 11 |
|
SV Erzhausen | 33 | 11 | 8 | 14 | 45:54 | -9 | 41 |
| 12 |
|
Viktoria Aschaffenburg | 33 | 11 | 7 | 15 | 45:53 | -8 | 40 |
| 13 |
|
KSV Baunatal | 33 | 10 | 10 | 13 | 38:48 | -10 | 40 |
| 14 |
|
SG Bruchköbel | 33 | 11 | 7 | 15 | 46:60 | -14 | 40 |
| 15 |
|
Eintracht Frankfurt II | 33 | 9 | 12 | 12 | 44:41 | 3 | 39 |
| 16 |
|
FSV Steinbach | 33 | 10 | 8 | 15 | 35:46 | -11 | 38 |
| 17 |
|
Germania Ober-Roden | 33 | 9 | 5 | 19 | 37:65 | -28 | 32 |
| 18 |
|
TSG Wattenbach | 33 | 2 | 4 | 27 | 25:85 | -60 | 10 |
