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| 22.02.1981 | Hellweg Lütgendortmund | - | Hammer SpVg | 0:0 | ||
| Bünder SV | - | SV Holzwickede | 1:0 | |||
| VfL Gevelsberg | - | 1. FC Paderborn | 3:1 | |||
| FC Gütersloh | - | Teutonia Lippstadt | 2:2 | |||
| Westfalia Herne | - | STV Horst-Emscher | 3:3 | |||
| VfB Waltrop | - | Eintracht Recklinghausen | 3:0 | |||
| SuS Hüsten 09 | - | DSC Wanne-Eickel | 1:1 | |||
| TuS Schloß-Neuhaus | - | Sportfreunde Siegen | 1:0 | |||
| VfB Rheine | - | VfB Altena | 6:0 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
VfB Rheine | 24 | 13 | 7 | 4 | 54:28 | 26 | 33:15 |
| 2 |
|
1. FC Paderborn | 24 | 15 | 3 | 6 | 48:28 | 20 | 33:15 |
| 3 |
|
VfL Gevelsberg | 24 | 12 | 8 | 4 | 51:29 | 22 | 32:16 |
| 4 |
|
FC Gütersloh | 24 | 12 | 6 | 6 | 46:28 | 18 | 30:18 |
| 5 |
|
DSC Wanne-Eickel | 24 | 10 | 9 | 5 | 57:35 | 22 | 29:19 |
| 6 |
|
Sportfreunde Siegen | 24 | 11 | 6 | 7 | 40:32 | 8 | 28:20 |
| 7 |
|
Hammer SpVg | 24 | 11 | 6 | 7 | 44:38 | 6 | 28:20 |
| 8 |
|
TuS Schloß-Neuhaus | 24 | 11 | 4 | 9 | 43:37 | 6 | 26:22 |
| 9 |
|
VfB Waltrop | 24 | 10 | 5 | 9 | 38:37 | 1 | 25:23 |
| 10 |
|
Westfalia Herne | 24 | 8 | 9 | 7 | 36:35 | 1 | 25:23 |
| 11 |
|
Hellweg Lütgendortmund | 24 | 7 | 8 | 9 | 30:38 | -8 | 22:26 |
| 12 |
|
SuS Hüsten 09 | 24 | 6 | 9 | 9 | 25:33 | -8 | 21:27 |
| 13 |
|
Teutonia Lippstadt | 24 | 6 | 7 | 11 | 36:39 | -3 | 19:29 |
| 14 |
|
Bünder SV | 24 | 6 | 6 | 12 | 30:46 | -16 | 18:30 |
| 15 |
|
VfB Altena | 24 | 5 | 8 | 11 | 26:48 | -22 | 18:30 |
| 16 |
|
STV Horst-Emscher | 24 | 5 | 6 | 13 | 28:61 | -33 | 16:32 |
| 17 |
|
Eintracht Recklinghausen | 24 | 3 | 9 | 12 | 31:54 | -23 | 15:33 |
| 18 |
|
SV Holzwickede | 24 | 3 | 8 | 13 | 28:45 | -17 | 14:34 |
