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| 21.11.1965 | 15:30 | BSC Oppau | - | FK Pirmasens | 0:2 | |
| 15:30 | Phönix Bellheim | - | 1. FSV Mainz 05 | 0:4 | ||
| 15:30 | SV Weisenau | - | Wormatia Worms | 1:4 | ||
| 15:30 | SV Röchling Völklingen | - | VfR Frankenthal | 1:0 | ||
| 15:30 | Saar 05 Saarbrücken | - | SV Alsenborn | 1:1 | ||
| 15:30 | TuS Neuendorf | - | SV Südwest Ludwigshafen | 3:1 | ||
| 15:30 | 1. FC Saarbrücken | - | Eintracht Trier | 4:1 | ||
| 15:30 | Ludwigshafener SC | - | TSC Zweibrücken | 3:0 |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FSV Mainz 05 | 16 | 11 | 2 | 3 | 42:18 | 24 | 24:8 |
| 2 |
|
TuS Neuendorf | 16 | 11 | 1 | 4 | 48:28 | 20 | 23:9 |
| 3 |
|
1. FC Saarbrücken | 16 | 10 | 2 | 4 | 47:17 | 30 | 22:10 |
| 4 |
|
FK Pirmasens | 16 | 10 | 2 | 4 | 24:15 | 9 | 22:10 |
| 5 |
|
Saar 05 Saarbrücken | 16 | 7 | 5 | 4 | 23:18 | 5 | 19:13 |
| 6 |
|
Wormatia Worms | 16 | 8 | 2 | 6 | 30:23 | 7 | 18:14 |
| 7 |
|
VfR Frankenthal | 16 | 6 | 5 | 5 | 32:27 | 5 | 17:15 |
| 8 |
|
Phönix Bellheim | 16 | 7 | 2 | 7 | 20:22 | -2 | 16:16 |
| 9 |
|
SV Röchling Völklingen | 16 | 7 | 1 | 8 | 28:35 | -7 | 15:17 |
| 10 |
|
SV Alsenborn | 16 | 5 | 4 | 7 | 25:30 | -5 | 14:18 |
| 11 |
|
Ludwigshafener SC | 16 | 5 | 3 | 8 | 26:30 | -4 | 13:19 |
| 12 |
|
Eintracht Trier | 16 | 5 | 2 | 9 | 25:30 | -5 | 12:20 |
| 13 |
|
SV Südwest Ludwigshafen | 16 | 4 | 4 | 8 | 23:32 | -9 | 12:20 |
| 14 |
|
SV Weisenau | 16 | 5 | 1 | 10 | 34:45 | -11 | 11:21 |
| 15 |
|
TSC Zweibrücken | 16 | 3 | 3 | 10 | 21:42 | -21 | 9:23 |
| 16 |
|
BSC Oppau | 16 | 4 | 1 | 11 | 16:52 | -36 | 9:23 |
