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|
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| 19.11.2021 | 20:00 | Hammer SpVg | - | SV Schermbeck | 0:2 (0:1) | |
| 20.11.2021 | 14:30 | Sportfreunde Siegen | - | TuS Ennepetal | 3:3 (0:2) | |
| 14:30 | SC Paderborn 07 II | - | Westfalia Rhynern | 0:3 (0:2) | ||
| 14:30 | Preußen Münster II | - | Holzwickeder SC | 0:3 (0:1) | ||
| 14:30 | SpVgg Vreden | - | Viktoria Clarholz | 2:0 (0:1) | ||
| 14:30 | FC Gütersloh | - | 1. FC Kaan-Marienborn | 1:2 (0:1) | ||
| 15:00 | TuS Erndtebrück | - | ASC 09 Dortmund | 0:1 (0:1) | ||
| 17:00 | RSV Meinerzhagen | - | Westfalia Herne | 4:2 (4:1) | ||
| 15.12.2021 | 19:30 | TuS Haltern | - | SG Finnentrop/Bamenohl | 1:2 (0:1) | |
| 16.12.2021 | 19:30 | TSG Sprockhövel | - | SG Wattenscheid 09 | 4:1 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Kaan-Marienborn | 12 | 10 | 1 | 1 | 36:11 | 25 | 31 |
| 2 |
|
SC Paderborn 07 II | 12 | 9 | 1 | 2 | 37:11 | 26 | 28 |
| 3 |
|
SG Wattenscheid 09 | 12 | 9 | 0 | 3 | 24:17 | 7 | 27 |
| 4 |
|
Westfalia Rhynern | 13 | 8 | 0 | 5 | 37:19 | 18 | 24 |
| 5 |
|
ASC 09 Dortmund | 13 | 7 | 3 | 3 | 27:18 | 9 | 24 |
| 6 |
|
FC Gütersloh | 12 | 7 | 3 | 2 | 19:10 | 9 | 24 |
| 7 |
|
FCE Rheine | 12 | 7 | 0 | 5 | 21:22 | -1 | 21 |
| 8 |
|
TSG Sprockhövel | 13 | 6 | 2 | 5 | 33:23 | 10 | 20 |
| 9 |
|
Sportfreunde Siegen | 13 | 5 | 4 | 4 | 21:23 | -2 | 19 |
| 10 |
|
TuS Erndtebrück | 12 | 5 | 3 | 4 | 22:21 | 1 | 18 |
| 11 |
|
SV Schermbeck | 12 | 5 | 2 | 5 | 22:18 | 4 | 17 |
| 12 |
|
TuS Ennepetal | 12 | 4 | 4 | 4 | 24:25 | -1 | 16 |
| 13 |
|
SpVgg Vreden | 13 | 4 | 3 | 6 | 14:27 | -13 | 15 |
| 14 |
|
Preußen Münster II | 12 | 4 | 2 | 6 | 17:25 | -8 | 14 |
| 15 |
|
Holzwickeder SC | 13 | 4 | 1 | 8 | 14:31 | -17 | 13 |
| 16 |
|
TuS Haltern | 12 | 3 | 3 | 6 | 15:21 | -6 | 12 |
| 17 |
|
Hammer SpVg | 13 | 3 | 3 | 7 | 22:30 | -8 | 12 |
| 18 |
|
Viktoria Clarholz | 12 | 3 | 2 | 7 | 17:22 | -5 | 11 |
| 19 |
|
SG Finnentrop/Bamenohl | 12 | 2 | 5 | 5 | 15:26 | -11 | 11 |
| 20 |
|
RSV Meinerzhagen | 12 | 3 | 0 | 9 | 16:30 | -14 | 9 |
| 21 |
|
Westfalia Herne | 13 | 0 | 2 | 11 | 13:36 | -23 | 2 |
| Playoffs | |
| Relegation |
