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| 16.05.2008 | 18:45 | SV Roßbach | - | 1. FC Saarbrücken | 0:0 (0:0) | |
| 19:00 | Eintracht Trier | - | FC 08 Homburg | 3:1 (2:0) | ||
| 19:00 | SC Hauenstein | - | FK Pirmasens | 2:0 (0:0) | ||
| 19:30 | 1. FSV Mainz 05 II | - | TuS Mechtersheim | 3:2 (0:2) | ||
| 17.05.2008 | 15:30 | FV Engers 07 | - | EGC Wirges | 2:3 (2:2) | |
| 15:30 | SC 07 Idar-Oberstein | - | SF Köllerbach | 4:1 (1:1) | ||
| 15:30 | Wormatia Worms | - | Borussia Neunkirchen | 0:0 (0:0) | ||
| 16:00 | Rot-Weiß Hasborn | - | Eintracht Bad Kreuznach | 0:0 (0:0) | ||
| 17:00 | TuS Mayen | - | 1. FC Kaiserslautern II | 0:2 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FSV Mainz 05 II | 32 | 23 | 4 | 5 | 83:18 | 65 | 73 |
| 2 |
|
Eintracht Trier | 32 | 18 | 10 | 4 | 54:27 | 27 | 64 |
| 3 |
|
1. FC Saarbrücken | 32 | 18 | 8 | 6 | 68:32 | 36 | 62 |
| 4 |
|
1. FC Kaiserslautern II | 32 | 19 | 5 | 8 | 58:26 | 32 | 62 |
| 5 |
|
Wormatia Worms | 32 | 19 | 5 | 8 | 56:27 | 29 | 62 |
| 6 |
|
Borussia Neunkirchen | 32 | 18 | 4 | 10 | 42:24 | 18 | 58 |
| 7 |
|
FC 08 Homburg | 32 | 12 | 10 | 10 | 46:39 | 7 | 46 |
| 8 |
|
EGC Wirges | 32 | 13 | 7 | 12 | 42:43 | -1 | 46 |
| 9 |
|
SC Hauenstein | 32 | 11 | 10 | 11 | 43:45 | -2 | 43 |
| 10 |
|
FK Pirmasens | 32 | 11 | 9 | 12 | 42:46 | -4 | 42 |
| 11 |
|
SC 07 Idar-Oberstein | 32 | 11 | 5 | 16 | 42:51 | -9 | 38 |
| 12 |
|
SV Roßbach | 32 | 9 | 11 | 12 | 36:50 | -14 | 38 |
| 13 |
|
TuS Mayen | 32 | 10 | 6 | 16 | 49:56 | -7 | 36 |
| 14 |
|
TuS Mechtersheim | 32 | 9 | 7 | 16 | 48:71 | -23 | 34 |
| 15 |
|
SF Köllerbach | 32 | 8 | 7 | 17 | 34:64 | -30 | 31 |
| 16 |
|
Rot-Weiß Hasborn | 32 | 8 | 4 | 20 | 29:61 | -32 | 28 |
| 17 |
|
Eintracht Bad Kreuznach | 32 | 4 | 10 | 18 | 27:76 | -49 | 22 |
| 18 |
|
FV Engers 07 | 32 | 5 | 2 | 25 | 26:69 | -43 | 17 |
