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| H | FC Carl Zeiss Jena | - | Wolverhampton Wanderers | 0:1 (0:1) | ||
| R | Wolverhampton Wanderers | - | FC Carl Zeiss Jena | 3:0 (2:0) | ||
| H: 23.11.1971 14:00 | R: 08.12.1971 20:30 | Sieger: Wolverhampton Wanderers | ||||
| H | UT Arad | - | Vitória Setúbal | 3:0 (2:0) | ||
| R | Vitória Setúbal | - | UT Arad | 1:0 (0:0) | ||
| H: 24.11.1971 13:45 | R: 08.12.1971 21:00 | Sieger: UT Arad | ||||
| H | Rapid Wien | - | Juventus | 0:1 (0:1) | ||
| R | Juventus | - | Rapid Wien | 4:1 (1:1) | ||
| H: 24.11.1971 18:30 | R: 08.12.1971 14:30 | Sieger: Juventus | ||||
| H | Eintracht Braunschweig | - | Ferencvárosi TC | 1:1 (0:1) | ||
| R | Ferencvárosi TC | - | Eintracht Braunschweig | 5:2 (2:0) | ||
| H: 24.11.1971 20:00 | R: 08.12.1971 16:30 | Sieger: Ferencvárosi TC | ||||
| H | PSV Eindhoven | - | Lierse SK | 1:0 (0:0) | ||
| R | Lierse SK | - | PSV Eindhoven | 4:0 (1:0) | ||
| H: 24.11.1971 20:00 | R: 08.12.1971 20:00 | Sieger: Lierse SK | ||||
| H | St. Johnstone FC | - | Željezničar Sarajevo | 1:0 (0:0) | ||
| R | Željezničar Sarajevo | - | St. Johnstone FC | 5:1 (3:1) | ||
| H: 24.11.1971 20:30 | R: 08.12.1971 15:30 | Sieger: Željezničar Sarajevo | ||||
| H | AC Milan | - | Dundee FC | 3:0 (1:0) | ||
| R | Dundee FC | - | AC Milan | 2:0 (1:0) | ||
| H: 24.11.1971 20:45 | R: 08.12.1971 20:30 | Sieger: AC Milan | ||||
| H | Tottenham Hotspur | - | Rapid Bucureşti | 3:0 (2:0) | ||
| R | Rapid Bucureşti | - | Tottenham Hotspur | 0:2 (0:0) | ||
| H: 08.12.1971 20:30 | R: 15.12.1971 12:30 | Sieger: Tottenham Hotspur | ||||
