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| H | Manchester United | - | Montpellier HSC | 1:1 (1:1) | ||
| R | Montpellier HSC | - | Manchester United | 0:2 (0:1) | ||
| H: 06.03.1991 | R: 19.03.1991 | Sieger: Manchester United | ||||
| H | Legia Warszawa | - | Sampdoria | 1:0 (1:0) | ||
| R | Sampdoria | - | Legia Warszawa | 2:2 (0:1) | ||
| H: 06.03.1991 | R: 20.03.1991 | Sieger: Legia Warszawa | ||||
| H | Dinamo Kiev | - | FC Barcelona | 2:3 (1:2) | ||
| R | FC Barcelona | - | Dinamo Kiev | 1:1 (0:0) | ||
| H: 06.03.1991 | R: 20.03.1991 | Sieger: FC Barcelona | ||||
| H | RFC Liège | - | Juventus | 1:3 (0:2) | ||
| R | Juventus | - | RFC Liège | 3:0 (3:0) | ||
| H: 06.03.1991 | R: 20.03.1991 | Sieger: Juventus | ||||
